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Initiates anti-CD27 Phase I trial in advanced solid tumors
March 5, 2018
By: Kristin Brooks
Managing Editor, Contract Pharma
Aduro Biotech, Inc. has earned a $3 million development milestone under its worldwide licensing agreement with Merck for the initiation of a Phase I trial of its anti-CD27 antibody. The Phase I trial will evaluate the safety and pharmacokinetics of the anti-CD27 antibody when administered alone and in combination with pembrolizumab in adults with advanced solid tumors. CD27 is a co-stimulatory receptor expressed on different immune cells, such as T-lymphocytes and NK (natural killer) cells. I...
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